Title of article
The Mechanism and Regulation of Chromosomal V(D)J Recombination
Author/Authors
Craig H Bassing، نويسنده , , Wojciech Swat، نويسنده , , Frederick W. Alt، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
11
From page
45
To page
55
Abstract
V(D)J recombination is of fundamental importance to the generation of diverse antigen receptor repertoires. We review our current understanding of the V(D)J recombination reaction and how it is regulated during lymphocyte development. We also discuss how defects in the mechanism or regulation of V(D)J recombination can lead to human disease.
Journal title
CELL
Serial Year
2002
Journal title
CELL
Record number
1017743
Link To Document