• Title of article

    A MAPK Scaffold Lends a Helping Hand

  • Author/Authors

    Markus A. Seeliger، نويسنده , , John Kuriyan، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    3
  • From page
    994
  • To page
    996
  • Abstract
    The scaffold proteins of signaling pathways are thought to act as passive tethering devices bringing together catalytic components of signaling cascades. now reveal that in the budding yeast the scaffold protein Ste5 acts as an allosteric activator of the mitogen-activated protein kinase Fus3, rendering it competent to be a kinase substrate for signal transmission.
  • Journal title
    CELL
  • Serial Year
    2009
  • Journal title
    CELL
  • Record number

    1019664