Title of article
Giving Alzheimerʹs the Old One-Two
Author/Authors
Michael S. Wolfe، نويسنده , , Dennis J. Selkoe، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
194
To page
196
Abstract
A dual goal for treating Alzheimerʹs disease (AD) is to decrease deposition of neurotoxic amyloid β-peptide in the brain and to boost repair of damaged neurons. now show that SIRT1 may mediate both processes by deacetylating the transcription factor retinoic acid receptor β, a potential new therapeutic target for AD.
Journal title
CELL
Serial Year
2010
Journal title
CELL
Record number
1020351
Link To Document