Title of article
Wnt Signaling: Multivesicular Bodies Hold GSK3 Captive
Author/Authors
Christof Niehrs، نويسنده , , Sergio P. Acebron، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
1044
To page
1046
Abstract
Two key events in Wnt signal transduction, receptor endocytosis and inactivation of Glycogen Synthase Kinase 3 (GSK3), remain incompletely understood. discover that Wnt signaling inactivates GSK3 by sequestering the enzyme in multivesicular bodies, thus linking these two events and providing a new framework for understanding Wnt signaling.
Journal title
CELL
Serial Year
2010
Journal title
CELL
Record number
1020536
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