• Title of article

    Wnt Signaling: Multivesicular Bodies Hold GSK3 Captive

  • Author/Authors

    Christof Niehrs، نويسنده , , Sergio P. Acebron، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    1044
  • To page
    1046
  • Abstract
    Two key events in Wnt signal transduction, receptor endocytosis and inactivation of Glycogen Synthase Kinase 3 (GSK3), remain incompletely understood. discover that Wnt signaling inactivates GSK3 by sequestering the enzyme in multivesicular bodies, thus linking these two events and providing a new framework for understanding Wnt signaling.
  • Journal title
    CELL
  • Serial Year
    2010
  • Journal title
    CELL
  • Record number

    1020536