Title of article
PK-M2 Makes Cells Sweeter on HIF1
Author/Authors
Daniel A. Tennant، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
647
To page
649
Abstract
The transcription factor hypoxia-inducible factor 1 (HIF1) facilitates the induction of enzymes necessary for anaerobic glycolysis. now identify pyruvate kinase (PK)-M2 as an intriguing new interacting partner for HIF1, revealing a potential mechanism for the Warburg effect, an elevation in aerobic glycolytic metabolism frequently observed in cancer.
Journal title
CELL
Serial Year
2011
Journal title
CELL
Record number
1020698
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