Title of article
A New FOXO Pathway Required for Leukemogenesis
Author/Authors
James R. Downing، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
2
From page
669
To page
670
Abstract
In cancer, the FOXO family of transcription factors functions as tumor suppressors and is directly inactivated by oncogenic signaling through the PI3K/AKT pathway. Now, Skykes et al. (2011) identify a paradoxical requirement for FOXOs in the maintenance of leukemia-initiating cells.
Journal title
CELL
Serial Year
2011
Journal title
CELL
Record number
1020804
Link To Document