• Title of article

    Unlatched BAX Pairs for Death

  • Author/Authors

    Heather M. Lamb، نويسنده , , J. Marie Hardwick، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2013
  • Pages
    2
  • From page
    383
  • To page
    384
  • Abstract
    Self-interacting BAX proteins permeabilize outer mitochondrial membranes to trigger apoptotic cell death. Czabotar et al. present two revealing structures of BAX dimers: one dimer has an activator BH3 helix bound into its canonical cleft, and the other dimer exposes a planar hydrophobic face potentially critical for membrane interactions.
  • Journal title
    CELL
  • Serial Year
    2013
  • Journal title
    CELL
  • Record number

    1021542