• Title of article

    Structure Modeling Using Genetically Engineered Crosslinking

  • Author/Authors

    Kuntal Pal، نويسنده , , Karsten Melcher، نويسنده , , Millard H. Lambert and H. Eric Xu، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2013
  • Pages
    2
  • From page
    1207
  • To page
    1208
  • Abstract
    Class B G-protein-coupled receptors are exciting drug targets, yet the structure of a complete receptor bound to a peptide agonist has remained elusive. Coin et al. present a model of the receptor CRF1R bound to its native ligand based on partial structures and 44 spatial constraints revealed by new crosslinking approaches.
  • Journal title
    CELL
  • Serial Year
    2013
  • Journal title
    CELL
  • Record number

    1022019