• Title of article

    Tetherin: Holding On and Letting Go

  • Author/Authors

    Daniel Sauter، نويسنده , , Anke Specht، نويسنده , , Frank Kirchhoff، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    7
  • From page
    392
  • To page
    398
  • Abstract
    Mammalian cells are equipped with so-called “restriction factors” that suppress virus replication and help to prevent virus transmission from one species to another. This Essay discusses the host restriction factor tetherin, which blocks the release of enveloped viruses like HIV-1, and the factors evolved by primate lentiviruses, such as Vpu and Nef, that antagonize tetherinʹs action.
  • Journal title
    CELL
  • Serial Year
    2010
  • Journal title
    CELL
  • Record number

    1022098