Title of article
Comparison of Healing Effect of Aloe Vera Extract and Silver Sulfadiazine in Burn Injuries in Experimental Rat Model
Author/Authors
AKHOONDINASAB، MOHAMMAD REZA نويسنده , , Akhoondinasab، Motahhare نويسنده Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; , , Saberi، Mohsen نويسنده Research Center, Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran ,
Issue Information
دوفصلنامه با شماره پیاپی 5 سال 2014
Pages
6
From page
29
To page
34
Abstract
BACKGROUND
Wound healing is widely discussed in the medical literature. This study compared the healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model.
METHODS
Sixteen rats were randomly assigned to one of two groups, each group 8 rats. A deep second-degree burn on the lower back and 3rd degree burn on upper back of each rat were created with a standard burning procedure. Burns were dressed daily with aloe vera extract in group 2 and silver sulfadiazine in group 1. Response to treatment was assessed by digital photography during treatment until day 32. Histological parameters (PMN, epithelialization, fibrosis and angiogenesis) were assessed after biopsy of scar at the end of research.
RESULTS
Wound healing was more visible in aloe vera group. Also the speed of healing in aloe vera group was better than silver sulfadiazine group.
CONCLUSIONS
Based on our findings, aloe vera can be a therapy of choice for burn injuries.
Journal title
World Journal of Plastic Surgery
Serial Year
2014
Journal title
World Journal of Plastic Surgery
Record number
1037813
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