New versatile polydopamine coated functionalized magnetic nanoparticles

Polydopamine coated magnetite nanoparticles are functionalized with azido groups by reaction with 4-azidobutylamine. The resulting nanoparticles allow straight forward Cu-catalyzed “click”-reaction with alkynes. In this way practically interesting functions can be tethered to the nanoparticles as exemplified by introducing biotin, glucose, proline or dansyl. The nanoparticles exhibit superparamagnetic behavior.