Title of article
Forskolin Studies
Author/Authors
Dirk Behnke، نويسنده , , Lothar Hennig، نويسنده , , Matthias Findeisen، نويسنده , , Peter Welzel، نويسنده , , Dietrich Müller، نويسنده , , Michael Thormann، نويسنده , , Hans-J?rg Hofmann، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
15
From page
1081
To page
1095
Abstract
A new nucleophilic isoprenoid C5 reagent is introduced which allowed synthesis of an advanced and optically active forskolin intermediate in a very efficient way. In addition, docking experiments that are based on X-ray results indicate that there might exist forskolin analogues with improved properties as far as binding to adenylyl cyclases and synthetic accessibility are concerned.
Keywords
nucleophilic isoprenoid C5 reagent , forskolin intermediate , adenylyl cyclase
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080579
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