Title of article
A New Efficient Route to (±)-Physostigmine and (±)-Physovenine by Means of 5-exo Selective Aryl Radical Cyclization of o-Bromo-N-acryloylanilides
Author/Authors
Hiroyuki Ishibashi، نويسنده , , Tetsuya Kobayashi، نويسنده , , Noriko Machida، نويسنده , , Osamu Tamura، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
1469
To page
1473
Abstract
Bu3SnH-mediated aryl radical cyclization of o-bromo-N-acryloylanilides 16 and 17 proceeded in a 5-exo manner exclusively to give, in high yields, oxindoles 3 and 4, the key intermediates for the synthesis of (±)-physostigmine and (±)-physovenine, respectively.
Keywords
Anilides , Cyclization , indolines/indolinones , radicals and radical reactions
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080621
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