Title of article
Synthesis and Reactivity of 1-Pyrroline-5-carboxylate Ester 1-Oxides
Author/Authors
David StC. Black، نويسنده , , Gavin L. Edwards، نويسنده , , Richard H. Evans، نويسنده , , Paul A. Keller، نويسنده , , Sean M. Laaman، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
9
From page
1889
To page
1897
Abstract
Some C5 mono- and diester-substituted 1-pyrroline-1-oxides have been prepared via reductive cyclisation of the corresponding γ-nitro carbonyl compounds. Ethyl 2-phenyl-1-pyrroline-1-oxide-5-carboxylate 5c was regioselectively alkylated at C5. Acylation of this molecule occurs exclusively on the nitrone oxygen and leads to C3 substituted pyrrolines as the result of a hetero-Cope rearrangement.
Keywords
Nitrones , pyrrolines/pyrrolinones , rearrangements , Cyclisation
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080669
Link To Document