Title of article
A New Protocol for the Synthesis of N(1)-Unsubstituted 2-Substituted 2-Imidazolines
Author/Authors
Raymond C.F. Jones، نويسنده , , Paschalis Dimopoulos، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
14
From page
2061
To page
2074
Abstract
Lateral metallation at C-2(α) of 1-tert-butoxycarbonyl-2-methyl-2-imidazoline followed by reaction with a range of C-electrophiles and deprotection with TFA reliably affords N(1)-unsubstituted 2-substituted 2-imidazolines; P- or Se-electrophiles lead to 2-alkenyl-2-imidazolines via Wadsworth–Emmons or selenoxide elimination protocols.
Keywords
N(1)-unsubstituted imidazolines , 2-alkenyl imidazolines , Wadsworth–Emmons protocols , selenoxide elimination protocols
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080685
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