Title of article
Preparation of New Pyridoacridine Derivatives and Formal Synthesis of 11-Hydroxyascididemine
Author/Authors
Mercedes ?lvarez، نويسنده , , Lidia Feliu، نويسنده , , Wadi Ajana، نويسنده , , John A Joule، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
6
From page
3703
To page
3708
Abstract
The preparation of pyrido[2,3,4-kl]acridin-6-ones substituted at position 4 following our previous methodology is described. A new synthetic route for the preparation of aminopyridoacridone 16, used before for the synthesis of the 11-hydroxyascididemine, is described. The cytotoxic activity of pyridoacridones 19 and 20 in four cell lines is reported.
Keywords
pyridoacridines , marine alkaloids , cytotoxic compounds
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080857
Link To Document