Title of article
Et3B- and Et2Zn-Mediated Radical Additions to Glyoxylate Imines, Compared Stereoinductions
Author/Authors
Michèle P. Bertrand، نويسنده , , Stéphanie Coantic، نويسنده , , Laurence Feray، نويسنده , , Robert Nouguier، نويسنده , , Patricia Perfetti، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
11
From page
3951
To page
3961
Abstract
1,3-Stereoinduction in the addition of alkyl radicals to glyoxylic imines derived from various chiral amines has been investigated. New synthetic methodologies involving Et3B and Et2Zn as mediators have been compared. Dihydro-1,4-oxazin-2-one (2b) gave the highest d.e. but no chemoselectivity. Open chain analogues derived from β-alkoxyamines led to good stereoinduction when the reaction was performed with Et2Zn which is a bidentate complexing reagent.
Keywords
triethylborane diethylzinc , glyoxylate imines , radical additions
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080884
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