Title of article
Generation of Penems, Carbapenems and Aza Analogs of Cephems by the Addition of Heterocycles and Other Building Blocks to Azetinones
Author/Authors
Harry H. Wasserman، نويسنده , , Mingde Xia، نويسنده , , Andrew J. Carr، نويسنده , , William T. Han، نويسنده , , Miles G. Siegel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
9
From page
5621
To page
5629
Abstract
Addition of nucleophiles including heterocycles and precursors of vicinal tricarbonyls to azetinones generates building blocks incorporating potential electrophilic centers. Oxidation of these products provides reactive carbonyl units suitably located for reaction with the β-lactam NH yielding bicyclic products of biological interest.
Keywords
carbapenems , azetinones , penems
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081057
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