• Title of article

    Radical Cyclization in Heterocycle Synthesis. Part 10: A Concise Synthesis of (−)-Kainic Acid via Sulfanyl Radical Addition–Cyclization–Elimination Reaction

  • Author/Authors

    Okiko Miyata، نويسنده , , Yoshiki Ozawa، نويسنده , , Ichiya Ninomiya، نويسنده , , Takeaki Naito، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    9
  • From page
    6199
  • To page
    6207
  • Abstract
    Sulfanyl radical addition–cyclization–elimination of diallylamines in the presence of thiophenol and AIBN gave the 2,3,4-trisubstituted pyrrolidine in high yield. This reaction was extended to a radical cyclization using a catalytic amount of thiophenol. A successful application was demonstrated by the asymmetric synthesis of (−)-kainic acid.
  • Keywords
    Thiophenol , Radical cyclization , Pyrrolidine , kainic acid
  • Journal title
    Tetrahedron
  • Serial Year
    2000
  • Journal title
    Tetrahedron
  • Record number

    1081117

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1081117