Title of article
Indium-Mediated Reaction of 3-Bromo-3,3-difluoropropene and Bromodifluoromethylacetylene Derivatives with Aldehydes
Author/Authors
Masayuki Kirihara، نويسنده , , Tomofumi Takuwa، نويسنده , , Shinobu Takizawa، نويسنده , , Takefumi Momose، نويسنده , , Hideo Nemoto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
6
From page
8275
To page
8280
Abstract
Aldehydes reacted with 3-bromo-3,3-difluoropropene at the α-position in the presence of indium to afford 1-substituted-2,2-difluorobut-3-en-1-ols. Ketones and other electrophiles are inert under the examined conditions. The reaction of bromodifluoromethylacetylene derivatives with an aldehyde in the presence of indium provided difluorohomopropargylic alcohols. These reactions efficiently proceeded in polar solvents (water, DMF) under mild conditions.
Keywords
indium and compounds , fluorine and compounds
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081338
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