Title of article
Reductive Cleavage of Benzannelated Cyclic Ethers and Amines: Synthetic Applications
Author/Authors
Ugo Azzena، نويسنده , , Salvatore Demartis، نويسنده , , Luciano Pilo، نويسنده , , Elisabetta Piras، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
8
From page
8375
To page
8382
Abstract
Reduction of symmetrical intramolecular diarylmethyl ethers (3a and 8a) and amines (3b and 8b) with alkali metals in THF allows the generation of unsymmetrical oxy- or amino-functionalised arylmethyl organometallics. Such intermediates were successfully trapped with various electrophiles, allowing a new access to unsymmetrically 2,2′-disubstituted-1,1′-biaryls (5aa–5bf) and 1,8-disubstituted naphthalenes (10aa–10be).
Keywords
Amines , Ethers , lithium and compounds , carbanions , Reduction
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081350
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