Hydroboration and Suzuki–Miyaura Coupling Reactions with the Electronically Modulated Variant of an Ynamine: The Synthesis of (E)-β-Arylenamides

The first hydroboration of an 1-alkynylamide—the electronically modulated variant of an ynamine—is described. This hydroboration in combination with a Suzuki–Miyaura cross-coupling reaction with aryl bromides or aryl iodides allows a flexible synthesis of (E)-β-arylenamides and 3-(2′-amidovinyl)indoles with high degree of molecular diversity.