Title of article
Synthesis of Chiral Piperazinones as Versatile Scaffolds for Peptidomimetics
Author/Authors
Frank Rübsam، نويسنده , , Ralph Mazitschek، نويسنده , , Athanassios Giannis، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
7
From page
8481
To page
8487
Abstract
Chiral piperazinones were synthesized as conformationally restricted peptidomimetics starting from inexpensive and readily available d-glucosamine hydrochloride and amino acid methyl esters. Different synthetic strategies are devised to allow attachment of side chains imitating the parent peptide as shown for the RGD motif.
Keywords
peptide mimetics , piperazinones , biologically active compounds , Amino sugars
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081360
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