Title of article
A Novel Cardenolide Photoaffinity Label for the Na/K-ATPase
Author/Authors
J?rg Zotzmann، نويسنده , , Lothar Hennig، نويسنده , , Peter Welzel، نويسنده , , Dietrich Müller، نويسنده , , Claudia Sch?fer، نويسنده , , Stefan Zillikens، نويسنده , , Hermann Pusch، نويسنده , , Helfried G. Glitsch، نويسنده , , Ralf Regenthal، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
8
From page
9625
To page
9632
Abstract
A benzoylbenzoyloxy derivative of digitoxigenin has been prepared which is the first cardenolide with an affinity label in the lactone ring. It inhibits the Na+/K+-ATPase almost as effectively as digitoxigenin itself. The activity was lost when in addition a biotin tag was attached to ring A.
Keywords
Na , Benzophenone , K-ATPase , affinity label , Cardenolides
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081486
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