Title of article
Asymmetric synthesis of (+)-febrifugine and (+)-isofebrifugine using yeast reduction
Author/Authors
Yasuo Takeuchi، نويسنده , , Kumiko Azuma، نويسنده , , Kentaro Takakura، نويسنده , , Hitoshi Abe، نويسنده , , Hye Sook Kim، نويسنده , , Yusuke Wataya، نويسنده , , Takashi Harayama، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
1213
To page
1218
Abstract
The antimalarial agents febrifugine (d-1) and isofebrifugine (d-2) were synthesized from chiral 3-piperidinol (d-4), which was asymmetrically prepared by the yeast reduction of 3-piperidone derivatives (dl-3), with dynamic optical resolution.
Keywords
Reduction , antimalarial compounds , Asymmetric synthesis , Optical resolution
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1081682
Link To Document