Title of article
Preparation of α- and β-substituted alanine derivatives by α-amidoalkylation or Michael addition reactions under heterogeneous catalysis assisted by microwave irradiation
Author/Authors
Antonio de la Hoz، نويسنده , , Angel D??az-Ortiz، نويسنده , , Mar??a Victoria G?mez، نويسنده , , José Antonio Mayoral، نويسنده , , Andrés Moreno، نويسنده , , Ana Mar??a S?nchez-Migall?n، نويسنده , , Ester V?zquez، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
8
From page
5421
To page
5428
Abstract
Silica-supported Lewis acids are useful catalysts in conjunction with microwave irradiation for the synthesis of a range of alanine derivatives. Reaction of methyl α-acetamidoacrylate (1) with different heterocycles, such as furan (2), pyrrole (3), N-benzylpyrrole (4), indole (5) and pyrazole (6) and the carbocycle 1,3,5-trihydroxybenzene (7), led to several α-amino acid precursors.
Keywords
Amino acid , Microwave irradiation , Nucleophile
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082136
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