Title of article
The synthesis of (−)-Ambrox® starting from labdanolic acid
Author/Authors
Marjon G Bolster، نويسنده , , Ben J.M Jansen، نويسنده , , Aede de Groot، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
5657
To page
5662
Abstract
Iododecarboxylation of labdanolic acid (1), followed by dehydrohalogenation led to alkenes 4 and 12. Both compounds were converted into (1R,2R,4aS,8aS)-1-(2-hydroxyethyl)-2,5,5,8a-tetramethyldecahydro-2-naphthalenol (8), which was transformed via cyclization into (−)-Ambrox® (9).
Keywords
labdanolic acid , iododecarboxylation , Ambrox®
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082162
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