Title of article
Modified Pictet–Spengler reaction. A highly diastereoselective approach to 1,2,3-trisubstituted-1,2,3,4-tetrahydro-β-carbolines using perhydro-1,3-heterocycles
Author/Authors
Kamaljit Singh، نويسنده , , Prasant K Deb، نويسنده , , P Venugopalan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
11
From page
7939
To page
7949
Abstract
A flexible variant of the Pictet–Spengler reaction employing oxazinanes as synthetic equivalents of several carbonyl compounds has been developed. Using acid catalyzed one pot condensation of perhydro-1,3-heterocycles various 1,3-disubstituted and 1,2,3-trisubstituted-1,2,3,4-tetrahydro-β-carbolines (THBCs) have been synthesized diastereoselectively.
Keywords
carbonyl equivalent , Pictet–Spengler reaction , Oxazolidine , tetrahydro-?-carboline , Diastereoselectivity , oxazinane
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082406
Link To Document