Title of article
Studies on quinones. Part 34: The reaction of styrene with activated 1,4-benzoquinones: access to potential antiprotozoal pyranobenzoquinones
Author/Authors
Jaime A Valderrama، نويسنده , , David Pessoa-Mahana، نويسنده , , Ricardo A Tapia، نويسنده , , Antonieta Rojas de Arias، نويسنده , , Héctor Nakayama، نويسنده , , Susana Torres، نويسنده , , Jorge Miret، نويسنده , , Mar??a Elena Ferreira، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
8653
To page
8658
Abstract
Styrene reacts with highly electrophilic monosubstituted 1,4-benzoquinones to provide pyranobenzoquinone and phenanthrene derivatives, depending on the nature of the quinone substituent. The participation of transient Diels–Alder adduct intermediates in these reactions and their thermal-induced rearrangements are discussed. The in vitro antiparasital effects of the pyranobenzoquinones against Trypanosoma cruzi and Leishmania spp. are reported.
Keywords
pyranobenzoquinones , Diels–Alder adduct rearrangements , antiparasital activity
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082478
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