Title of article
An improved preparation of epoxides from carbonyl compounds by using diiodomethane/methyllithium: synthetic applications
Author/Authors
José M Concell?n، نويسنده , , Humildad Cuervo، نويسنده , , Ram?n Fern?ndez-Fano، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
5
From page
8983
To page
8987
Abstract
Synthesis of epoxides starting from different carbonyl compounds is easily carried out by using a diiodomethane and methyllithium at 0°C and a short reaction time. Starting from α-aminoaldehydes the reaction affords amino epoxides, with high diastereoselectivity. The products were transformed into 1,3-diaminoalkan-2-ols by treatment with different amines.
Keywords
Epoxides , diastereoselection , iodomethyllithium , Carbonyl compounds
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082519
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