• Title of article

    Modified nucleosides. A general and diastereoselective approach to N,O-psiconucleosides

  • Author/Authors

    Daniela Iannazzo، نويسنده , , Anna Piperno، نويسنده , , Venerando Pistarà، نويسنده , , Antonio Rescifina، نويسنده , , Roberto Romeo، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    7
  • From page
    581
  • To page
    587
  • Abstract
    An efficient reaction route towards the new class of N,O-psiconucleosides has been designed, based on the 1,3-dipolar cycloaddition of C-[(tert-butyldiphenylsilyl)oxy]methyl-N-methyl nitrone with ethyl 2-acetyloxyacrylate, followed by nucleosidation. The process has been successfully applied to all pyrimidine and purine nucleobases.
  • Keywords
    modified nucleosides , psiconucleosides , 3-dipolar cycloaddition , PM3 calculation , 1
  • Journal title
    Tetrahedron
  • Serial Year
    2002
  • Journal title
    Tetrahedron
  • Record number

    1082730