Title of article
Reactions of aromatic methyl ketimines with halonitriles as a new route to pyrimidines with two polyhaloalkyl groups
Author/Authors
Vyacheslav Ya Sosnovskikh، نويسنده , , Boris I Usachev، نويسنده , , Gerd-Volker R?schenthaler، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
1375
To page
1379
Abstract
N-Isopropyl-(1-phenylethylidene)amine reacts with trichloroacetonitrile to give 1-azabutadiene derivative, which undergoes a double addition reaction with a variety of halonitriles affording fluoro- and chloro-containing pyrimidines. Pyrimidines with two polyhaloalkyl groups were obtained by the reaction of methyl ketimines with an excess of trichloroacetonitrile, trifluoroacetonitrile and 2,2,3,3-tetrafluoropropionitrile.
Keywords
pyrimidines with two polyhaloalkyl groups , methyl ketimines , Trichloroacetonitrile , 2 , 2 , 3 , 3-tetrafluoro-propionitrile , CCl3-containing ?-aminovinyl imine and ketone , trifluoroacetonitrile
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1082811
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