Title of article
Separation of enantiomers by lipase-catalyzed fluorous-phase delabeling
Author/Authors
Sauda M Swaleh، نويسنده , , Benno Hungerhoff، نويسنده , , Helmut Sonnenschein، نويسنده , , Fritz Theil، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
4085
To page
4089
Abstract
Simultaneous enantiomer-selective fluorous-phase delabeling and kinetic resolution was achieved by lipase-catalyzed alcoholysis of highly fluorinated esters of racemic alcohols. The separation of the fast-reacting delabeled enantiomers and the slow-reacting fluorous-phase labeled enantiomers was performed very efficiently by partition in an organic/fluorous biphasic solvent system.
Keywords
Kinetic resolution , perfluorinated solvents , Lipase , fluorous phase
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1083097
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