The reactions of 2-(chloroseleno)benzoyl chloride with nucleophiles

The reactions of 2-(chloroseleno)benzoyl chloride with N, O and S nucleophiles such as alkanols, aminoalkanols, phenols, thiols, aminothiols and thiophenols have been investigated. It was found that the most reactive was a primary amino group which simultaneously underwent selenenylation–acylation. Less reactive hydroxy and thiol groups were selenenylated and/or acylated depending on the structure of the substrate and reaction conditions.