Title of article
Synthesis of (−)-TAN1251A using 4-hydroxy-l-proline as a chiral source
Author/Authors
Shinji Nagumo، نويسنده , , Aoi Matoba، نويسنده , , Yusuke Ishii، نويسنده , , Syunji Yamaguchi، نويسنده , , Noriaki Akutsu، نويسنده , , Hideto Nishijima، نويسنده , , Atsushi Nishida، نويسنده , , Norio Kawahara، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
7
From page
9871
To page
9877
Abstract
A new synthetic route of (−)-TAN1251A possessing an antimuscarinic activity was developed on the basis of alkylation of a trans-4-hydroxy-l-proline derivative and the subsequent construction of an azaspiro ring as key steps.
Keywords
trans-4-hydroxy-l-proline , anti-muscarinic activity , (?)-TAN1251A , Synthesis
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1083702
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