Title of article
One step synthesis of imidazole and benzimidazole acycloaromatic nucleoside analogs
Author/Authors
A Khalafi-Nezhad، نويسنده , , M.N. Soltani Rad and G.R. Nejabat، نويسنده , , G.H Hakimelahi، نويسنده , , B Mokhtari، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
10341
To page
10344
Abstract
A facile and rapid method for the synthesis of novel imidazole and benzimidazole aromatic acyclic nucleosides is described. Synchronous N-alkylation of imidazole or benzimidazole and potassium aryloxide with methylene iodide in the presence of triethylamine and a catalytic amount of tetrabutylammonium bromide (TBAB) in dry acetonitrile or acetone gave moderate yields of the acycloaromatic nucleoside analogs.
Keywords
Imidazole , acycloaromatic nucleosides , Benzimidazole
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1083757
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