Title of article
A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring
Author/Authors
Sandra Gemma، نويسنده , , Stefania Butini، نويسنده , , Caterina Fattorusso، نويسنده , , Isabella Fiorini، نويسنده , , Vito Nacci، نويسنده , , Katherine Bellebaum، نويسنده , , Down McKissic، نويسنده , , Ashima Saxena، نويسنده , , Giuseppe Campiani، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
7
From page
87
To page
93
Abstract
The synthesis of two new Huperzine A analogues is reported. Both products present an amino substituted benzo-fused system in place of the pyridone ring of the natural alkaloid. The synthetic strategy to the two analogues is based on three different key palladium-catalyzed steps, namely a carbonylation reaction, an epoxide isomerization and a bicycloannulation reaction.
Keywords
Palladium , Carbonylation , epoxide isomerization , bicycloannulation reaction
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1083780
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