Title of article
Four new andrographolide metabolites in rats
Author/Authors
Xiangjiu He، نويسنده , , Jiankuan Li، نويسنده , , Hao Gao، نويسنده , , Feng Qiu، نويسنده , , R.; Ke Hu، نويسنده , , Xiangmin Cui، نويسنده , , Xinsheng Yao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
6603
To page
6607
Abstract
Four new sulfonate metabolites of andrographolide, 14-deoxy-12(R)-sulfo andrographolide (Metabolite ), 14-deoxy-12(S)-sulfo andrographolide (Metabolite ), 14-deoxy-12(R)-sulfo-9(S)-andrographolide (Metabolite ) and 14-sulfo isoandrographolide (Metabolite ), were isolated from urine and feces in rats. Their structures were elucidated by chemical and spectroscopic analyses. These four metabolites were formed through a rare metabolic reaction and were all new compounds.
Keywords
sulfonate compounds , andrographolide , metabolites in rats
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084218
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