Title of article
Total synthesis of the polyenoyltetramic acid polycephalin C
Author/Authors
Deborah A Longbottom، نويسنده , , Angus J Morrison، نويسنده , , Darren J Dixon، نويسنده , , Steven V Ley، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
12
From page
6955
To page
6966
Abstract
The total synthesis of the polyenoyltetramic acid polycephalin C is described. Key steps of the synthesis include a double Swern oxidation, double Takai reaction and a double Stille reaction. In addition, the absolute stereochemistry of the ring junction has been determined by synthesis of both isomers and comparison of their CD spectra with natural polycephalin C.
Keywords
tetramic acids , Lactams , Swern oxidation , natural product synthesis , Takai reaction
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084245
Link To Document