Title of article
Total synthesis of (±)-tangutorine and chiral HPLC separation of enantiomers
Author/Authors
Tiina Putkonen، نويسنده , , Arto Tolvanen، نويسنده , , Reija Jokela، نويسنده , , Salvatore Caccamese، نويسنده , , Nunziatina Parrinello، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
7
From page
8589
To page
8595
Abstract
The first total synthesis of racemic tangutorine, a novel indole alkaloid, was performed in 7 steps. The key reactions, dithionite reduction and acidic cyclization provided easy access with good yields to the tangutorine skeleton. Comprehensive NMR spectroscopic data of new compounds are given. Chiral HPLC separation of enantiomers is reported.
Keywords
Natural products , Indole alkaloids , 3-?] quinolizidine
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084412
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