Title of article
Regioselective reduction of N-alkyl-3-sulfonyl glutarimides to δ-lactams. Formal synthesis of (±)-paroxetine and (±)-tacamonine
Author/Authors
Chung-Yi Chen، نويسنده , , Bo-Rui Chang، نويسنده , , Min-Ruei Tsai، نويسنده , , Meng-Yang Chang، نويسنده , , Nein-Chen Chang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
9383
To page
9387
Abstract
A convenient method for the preparation of 4- or 5-substituted 3-sulfonyl-δ-lactams via regioselective reduction of N-alkyl-3-sulfonyl glutarimides is described. Formal synthesis of (±)-paroxetine and (±)-tacamonine is also reported.
Keywords
tacamonine , glutarimide , regioselective reduction , ?-lactam , Paroxetine
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084483
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