Title of article
Titanium-promoted enantioselective diethylzinc addition to benzaldehyde in the presence of C2-symmetrical bis(camphorsulfonamide) ligands
Author/Authors
Tomasz Bauer، نويسنده , , Joanna Gajewiak، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
10009
To page
10012
Abstract
The synthesis of several C2-symmetric bissulfonamides is described, starting from camphorsulfonyl chloride and various aromatic as well as aliphatic diamines. These compounds have been used as ligands for titanium tetraisopropoxide promoted diethylzinc addition to benzaldehyde. The best enantiomeric excess obtained in this study was 67%. The stereochemical outcome of the reaction is highly influenced both by the structure of ligand and the reaction parameters.
Keywords
Enantioselectivity , camphorsulfonamides , Diethylzinc , titanium tetrapropoxide
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084549
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