Title of article
First synthesis of methyl 3-amino-4-(het)aryl-1H-pyrrole-2-carboxylates as useful scaffolds in medicinal chemistry
Author/Authors
Christophe Rochais، نويسنده , , Vincent Lisowski، نويسنده , , Patrick Dallemagne، نويسنده , , Sylvain Rault، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
2267
To page
2270
Abstract
The preparation of new methyl 4-(het)aryl-3-amino-1H-pyrrole-2-carboxylates was achieved starting from commercial arylacetonitriles. This four steps synthesis afforded with good yields interesting building-blocks useful in the access to many nitrogen heterocycles with potential therapeutic interest.
Keywords
Aminoarylypyrrolecarboxylates , Enamine , Diethylaminomalonate , Cyclisation
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085021
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