Title of article
2-Substituted-3,7-dinitro-11-oxatricycloundec-9-ene: an approach towards the synthesis of Ergot alkaloids
Author/Authors
Shatha Younis Mahmood، نويسنده , , Marie-Christine Lallemand، نويسنده , , Lina Sader-Bakaouni، نويسنده , , Olivier Charton، نويسنده , , Philippe Vérité، نويسنده , , Hanh Dufat، نويسنده , , Francois Tillequin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
5105
To page
5110
Abstract
A simple and versatile method for the preparation of various ergoline or secoergoline skeleton, using 2-substituted-3,7-dinitro-11-oxatricycloundec-9-ene as key intermediates, is described. The key step involves an IMDAF reaction with an excellent stereocontrol. This novel synthetic route provides new cycloadducts as useful scaffolds for Ergot alkaloids synthesis.
Keywords
Secoergoline , Lysergic acid , IMDAF , Ergot alkaloids , Ergoline , Oxatricycloundec-9-ene compounds
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085684
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