Title of article
A new synthesis of 3-hydroxy-2,3-dihydro-1,4-benzodioxin-2-carboxamides and 3-aminomethylene-1,4-benzodioxin-2(3H)-one derivatives
Author/Authors
C Bozzo، نويسنده , , M.D Pujol، نويسنده , , X Solans، نويسنده , , M Font-Bardia، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
10
From page
1227
To page
1236
Abstract
The 1,4-benzodioxin-2-carboxylic esters or carboxamides react with nucleophilic amines to give access to 3-hydroxy-2,3-dihydro-1,4-benzodioxin-2-carboxamides and 3-aminomethyn-1,4-benzodioxin-2(3H)-one precursors of potential therapeutical compounds. The basic environment (K2CO3 or amine) facilitates the process.
Keywords
4-benzodioxin-2-carboxamides , 4-benzodioxin-2-carboxylic esters , 1 , 3-disubstituted-1 , 4-benzodioxines , Michael addition , 1 , 2
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1087532
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