Title of article
Synthesis and antiviral activity of scopadulcic acids analogues
Author/Authors
Manuel Arn?، نويسنده , , Liliana Betancur-Galvis، نويسنده , , Juan G. Bueno-Sanchez، نويسنده , , Miguel A. Gonz?lez، نويسنده , , Ram?n J. Zaragoz?، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
10
From page
6455
To page
6464
Abstract
The synthesis and antiviral properties of several scopadulcic acid analogues functionalized at C-6/C-7 and C-13 is reported. The preparation of advanced intermediates for the synthesis of scopadulcic acid B/scopadulciol analogues is also described. The biological study revealed the importance of polar groups at C-13, while the stereochemistry at C-8 was not critical for activity.
Keywords
scopadulcic , diterpenes , thyrsifloranes , Antivirals , thyrsiflorin
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1088122
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