Title of article
Palladium-catalyzed homocoupling of aryl halides in the presence of fluoride
Author/Authors
W. Michael Seganish، نويسنده , , Molly E. Mowery، نويسنده , , Shaundra Riggleman، نويسنده , , Philip DeShong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
2117
To page
2121
Abstract
This report describes the fluoride-mediated homocoupling of aryl iodides and bromides catalyzed by palladium(0). This coupling protocol is tolerant of electron-donating and electron-withdrawing substitutents on the aryl halide, as well as ortho substitution. Optimum reaction conditions entail 10 mol% Pd(dba)2, 3 equiv of tetrabutyl ammonium fluoride (TBAF) in DMF at 90 °C.
Keywords
Tetrabutylammonium fluoride , Aryl homocoupling , Ullmann coupling
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088442
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