Total synthesis of marine bisindole alkaloids, (+)-hamacanthins A, B and (−)-antipode of cis-dihydrohamacanthin B

The total synthesis of the marine bisindole alkaloids, (+)-hamacanthins A () and B (), and (−)-antipode of cis-dihydrohamacanthin B () was achieved by transamidation–cyclization of N-(2-aminoethyl)-2-oxoethanamide derived from (S)-indolylglycinol .