Title of article
Free radical synthesis of benzofused tricyclic β-lactams by intramolecular cyclization of 2-azetidinone-tethered haloarenes
Author/Authors
Benito Alcaide، نويسنده , , Pedro Almendros، نويسنده , , Alberto Rodr?guez-Vicente، نويسنده , , M. Pilar Ruiz، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
12
From page
2767
To page
2778
Abstract
o-Halogenophenyl- and o-halogenobenzyl-4-alkenyl-β-lactams can be prepared both in the racemic form and in optically pure form using the ketene–imine cyclization. These 2-azetidinone-tethered haloarenes were used for the regio- and stereoselective preparation of benzofused tricyclic β-lactams including benzocarbapenems and benzocarbacephems via intramolecular aryl radical cyclisation.
Keywords
Nitrogen heterocycles , Radical reactions , Cycloaddition , polycycles , Lactams
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088506
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