Title of article
Synthesis of functionalized m-bistrifluoromethylbenzenes via cyclocondensation of 1,1,1,5,5,5-hexafluoroacetylacetone with enamines
Author/Authors
Dmitriy M. Volochnyuk، نويسنده , , Alexander N. Kostyuk، نويسنده , , Dmitriy A. Sibgatulin، نويسنده , , Alexander N. Chernega، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
9
From page
2839
To page
2847
Abstract
The reaction of 1,1,1,5,5,5-hexafluoroacetylacetone with push–pull enamines having a methyl group at the α-position was investigated. It was found that the reaction is sensitive both to the structure of enamines and to reaction conditions. As a result, a set of bistrifluoromethyldialkylanilines and ethyl bistrifluoromethylsalicylate was prepared. Plausible mechanisms and factors influencing the course of the reaction are discussed.
Keywords
1 , 5 , 5-Hexafluoroacetylacetone , Cyclocondensation , Push–pull enamines , 5 , 1 , 1 , Trifluoromethylated benzenes
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088512
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